This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Citing articles on Web of Science (18)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

GABOR S. KOVACS, MD; J. DONALD HILL, MD; TORKEL ABERG, MD; ARY BLESOVSKY, MD; FRANK GERBODE, MD

AMA Arch Surg. 1966;93(5):813-823.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

PERIPHERAL cyanosis is a well known clinical sign in severe pulmonary embolism. The development of arterial hypoxia, however, has been described only recently.¹ The occurrence of this phenomenon has since been repeatedly confirmed and various etiologic factors have been suggested as its main cause (eg, alveolar hypoventilation, ventilation-perfusion abnormalities, decreased diffusing capacity of the lungs, pulmonary edema, venoarterial shunting).^2-14 Although the results obtained under different experimental conditions by different groups of investigators are difficult to compare, convincing evidence suggests that more than one factor might contribute at the same time or in sequence to the development of arterial desaturation.

This investigation was undertaken in order to study the dynamics of the development of arterial hypoxia in experimental pulmonary embolism and by separate application of the different causative factors establishing their role in arterial desaturation.

Four pathways were recognized in the development of arterial hypoxia following pulmonary embolus. The . . . [Full Text PDF of this Article]

Author Affiliations
SAN FRANCISCO

From the Department of Cardiovascular Surgery, Presbyterian Medical Center, and the Institute of Medical Sciences, San Francisco. Dr. Kovacs is presently with I Surgical Clinic, Medical University, Szeged, Hungary. Dr. Blesovsky is a Evarts A. Graham Travelling Fellow for 1965-1966 and holder of a travelling grant from The Wellcome Trust, London.

Footnotes
Read before the 14th Scientific Meeting of the North American Chapter of the International Cardiovascular Society, Chicago, June 25, 1966.

Reprint requests to Presbyterian Medical Center, San Francisco 94115 (Dr. Gerbode).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?