This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (30)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

GUSTAVO BOUNOUS, MD; ROBERT F. P. CRONIN, MD; FRASER N. GURD, MD

AMA Arch Surg. 1967;94(1):46-60.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

A MAJOR difficulty in the interpretation of experiments in shock is the variation of response from one animal species to another. In particular, the terminal mechanisms which lead to death appear to differ when one compares the human with the intact laboratory animal. There is no doubt as to the universal dependence of vertebrates upon the delivery of oxygen and metabolic substrates to the membranes of the individual cells via the circulation of the blood. There is no doubt that a prolonged deficiency of capillary circulation results in reversion to an anaerobic metabolic state and a gradual loss of tissue viability. It is in the course of this progression toward sequential organ failure that the major species differences between the dog, the rat, and man became more clearly demarcated.

Dogs submitted to the usual hemorrhagic shock procedures by the techniques of Fine or Wiggers are brought to a standard stage . . . [Full Text PDF of this Article]

Author Affiliations
MONTREAL

From the McGill-Montreal General Hospital University Surgical Clinic, Montreal.

Footnotes
Submitted for publication Aug 11, 1966.

Reprint requests to Department of Surgery, Montreal General Hospital, Montreal 25, Quebec, Canada (Dr. Gurd).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?