This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (53)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Report of Two Cases and Review of the Literature

Charles S. Eby, MD; Michael J. Brennan, MD; Gerald Fine, MD

AMA Arch Surg. 1967;94(2):223-230.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

IN 1948, Stewart and Treves¹ described six cases of a previously unrecognized clinicopathological entity—lymphangiosarcoma in postmastectomy lymphedema. Eighty-eight similar cases^2-58 from the literature and three unpublished cases (written communications from W. R. Nelson and W. D. McCarthy, on Jan 26, 1966, and April 29, 1966, respectively) have been variously designated angiosarcoma, angioplastic sarcoma, malignant lymphostatic endothelioma, and lymphangioendothelioma and hemangioendothelioma, reflecting the differences in concept regarding the tumor's histogenesis. In addition, 15 cases^{10,19,30,33,50,59-69} of lymphangiosarcoma arising in primary or secondary lymphedematous extremities unassociated with breast carcinoma have been reported.

This is a report of two postmastectomy lymphangiosarcomas (Stewart-Treves syndrome) studied at the Henry Ford Hospital since 1960 and a review of the literature, including follow-up information on 19 of the 112 cases.

Report of Cases

CASE 1.

—A 68-year-old white woman had lymphedema of the right arm for 18 years following a radical mastectomy and preoperative and . . . [Full Text PDF of this Article]

Author Affiliations
Detroit

From the departments of dermatology, oncology, and pathology, Henry Ford Hospital, Detroit. Dr. Brennan is presently president of the Michigan Cancer Foundation.

Footnotes
Submitted for publication Sept 6, 1966.

Reprint requests to 2799 W Grand Blvd, Detroit 48202 (Dr. Eby).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?