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Edward M. Pallette, MD; Edward C. Pallette, MD; Robert W. Harrington, MD

AMA Arch Surg. 1967;94(6):803-810.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

SEVERAL reports concerning chronic inflammatory infiltrations of the small bowel mesentery and retroperitoneum have been published. Xanthogranulomatous obstruction of the colon,¹ sclerosing retroperitonitis with ureteral obstruction,² and isolated mesenteric panniculitis³ would at first appear to be distinctly separate pathological entities. It is our opinion, however, that each represents a different symptom complex resulting from the same nonspecific tissue reaction.

The process seems to begin with a fatty tissue injury which results in a granulomatous cellular reaction followed by fibrosis. The resulting clinical picture is determined by the envelopment and gradual narrowing of the tubular structures that lie within the mass. Gross and microscopic descriptions of tissue obtained from patients with these several afflictions have shown consistent similarities, suggesting that clinical differences are chiefly due to location, extent, and duration of the process. We postulate that these and similar syndromes are manifestations of sclerosing lipogranulomatosis.

Report of Cases . . . [Full Text PDF of this Article]

Author Affiliations
Los Angeles

From the Department of Surgery, St. Vincent's Hospital, Los Angeles.

Footnotes
Submitted for publication Dec 10, 1966.

Reprint requests to 3875 Wilshire Blvd, Los Angeles 90005 (Edward M. Pallette, MD).

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