 |
|
Controlled Hypotension for Uncontrolled Hemorrhage
Robert W. Hopkins, MD;
Richard B. Fratianne, MD;
Jerome S. Abrams, MD;
F. A. Simeone, MD
AMA Arch Surg. 1967;95(3):517-530.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
|
|
|
HYPOTENSION induced and controlled by the administration of trimethaphan camsylate has been used as an adjunct to the therapy of patients with massive hemorrhage under circumstances in which bleeding was not readily controlled and did not spontaneously cease. The hypotensive agent was used to accomplish two principal objectives: (1) to lower the arterial pressure and thereby to reduce bleeding while restoring the blood volume to normal levels by transfusion, and (2) to prevent excessive vasoconstriction, the normal physiologic response to hypotention, with the consequent impairment of flow of blood through capillaries.
The findings in patients in whom deliberate hypotension was used in the management of severe bleeding have been reported previously.1 An additional 15 patients have been treated with controlled hypotension since that time.
Methods
Clinical observations have been made during 22 episodes of massive bleeding in 20 patients in whom hypotension was deliberately induced by the use of
. . . [Full Text PDF of this Article]
Author Affiliations
Cleveland
From the Metropolitan General Hospital, and Western Reserve University, School of Medicine, Cleveland.
Footnotes
Submitted for publication March 15, 1967.
Read before the 24th annual meeting of the Central Surgical Association, Pittsburgh, Feb 24, 1967.
Reprint requests to 3395 Scranton Rd, Cleveland 44109 (Dr. Hopkins).
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
|
