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S. Frank Redo, MD; Mary Allen Engle, MD; Kathryn H. Ehlers, MD; Peter B. Farnsworth, MD

AMA Arch Surg. 1967;95(5):717-723.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

ATRESIA of the mitral valve, often with associated aortic valve atresia or hypoplasia of the aorta, is an uncommon congenital cardiac defect that leads to death in early infancy. In her classic monograph, Maude Abbott¹ reported that five specimens were encountered in 1,000 postmortem examinations of patients with congenital heart disease. The lesion has been estimated to occur once in 50,000 children.²

The etiology of this malformation is not known. Among the theories advanced are: that the usual bending of the primary cardiac tube is distorted, (Spitzer^3-5); that growth of the interventricular septum is maldirected (Moenckeberg⁶); that the septum primum and the endocardial cushion are fused (Brockman⁷); that the truncus arteriosus is unevenly partitioned (Castrovinci and Cucci⁸); and that it is the result of fetal endocarditis (Farber and Hubbard⁹).

Diagnosis is difficult since the anomaly must be differentiated from all conditions that . . . [Full Text PDF of this Article]

Author Affiliations
New York

From The New York Hospital, Cornell University Medical Center, Department of Surgery and Pediatrics, New York.

Footnotes
Submitted for publication July 26, 1967.

Read before the 15th Scientific Meeting of the North American Chapter of the International Cardiovascular Society, Atlantic City, NJ, June 16, 1967.

Reprint requests to 525 E 68th St, New York 10021 (Dr. Redo).

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