This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (6)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Peter Dineen, MD

AMA Arch Surg. 1968;96(2):219-221.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THERE have been several reports recently on the use of fusidate sodium in the treatment of infections caused by Staphylococcus aureus.¹ One of the most difficult problems in the evaluation of any new antimicrobial agent is to find suitable situations in which to assess the efficacy of the drug. The optimal situation is one in which the only active therapy is the agent under study. Bacteremia (endocarditis) and pneumonia are two disease states which lend themselves readily for clinical testing of drugs. Most chemotherapeutic agents (with the exception of some specifically for the urinary tract or skin) have been accepted or rejected on their ability to cure or improve these infections. In the therapy of surgical microbial diseases, clinical evaluation of efficacy is much more complex. The majority of the cases represent a localization of purulent material some place in the body. In these situations incision and drainage of . . . [Full Text PDF of this Article]

Author Affiliations
New York

From the Microbiological Research Laboratory, Department of Surgery, New York Hospital-Cornell Medical Center, New York.

Footnotes
Submitted for publication July 24, 1967.

Reprint request to Department of Surgery, North Shore Hospital, Valley Rd, Manhasset, NY 11030 (Dr. Dineen).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?