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Experimental and Clinical Use of Adhesive on Parenchymatous Organs
Kazuo Ota, MD;
Shyunichi Mori, MD;
Katsumi Mizuno, MD;
Tsunamasa Inou, MD
AMA Arch Surg. 1968;96(2):231-236.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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HEMORRHAGE from the cut surface is inevitable in the partial resection of liver, pancreas, kidney and spleen. In partial hepatectomy and in partial pancreatectomy the leak of the bile or the pancreatic juice further complicates the cut surface. If the leak continues persistently after operation, it is detrimental to the peritoneum. The use of needles and sutures for stopping the hemorrhage and the leak of the bile or the pancreatic juice may cause additional hemorrhage and the retardation of operation time. To solve this problem, an adhesive, 98% ethyl cyanoacrylate monomer, was used. We have reported that the replacement of methyl radical by the ethyl in the side chain of cyanoacrylate monomer significantly lessens histotoxicity1,2 and that n-butyl, 2-ethylhexyl and isopropyl monomers have no less histotoxicity than ethyl monomer on histologic examination.3
Experimental Surgery
Materials and Methods.
—Experimental animals were 12 mongrel dogs. The right lobe of the
. . . [Full Text PDF of this Article]
Author Affiliations
Tokyo
From the Second Department of Surgery, Tokyo University School of Medicine, Tokyo.
Footnotes
Submitted for publication July 24, 1967.
Reprint requests to Hongo 7-3-1, Bunkyo-ku, Tokyo (Dr. Ota).
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