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Effect on Gastric Secretion in Heidenhain Pouches With Innervated Excluded Antra

Michael Upsher, MD; Shoichi Kohatsu, MD; Harry A. Oberhelman, Jr., MD

AMA Arch Surg. 1968;96(2):277-280.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE relationship between the vagus nerves and the humoral phase of gastric secretion has been a subject of considerable interest and controversy in recent years. Burstall and Schofield¹ found a small but detectable increase in Heidenhain pouch secretion in response to both psychic stimulation and insulin hypoglycemia utilizing special methods to elute the pouch contents. Oberhelman et al² demonstrated a definite increase in free acid concentration in Heidenhain pouch secretion in response to insulin hypoglycemia after excluding the innervated gastric antrum from the acid gastric secretion of the body and fundus of the stomach. They attributed this effect to the release of gastrin brought about by peristaltic activity of the antrum induced by vagalstimulation.

Chapman et al³ confirmed these findings in a similar preparation. In addition, they observed that antroneurolysis abolished the secretory response without affecting the motility response. Pe Thein and Schofield⁴ found similar acid . . . [Full Text PDF of this Article]

Author Affiliations
Palo Alto, Calif

From the Department of Surgery, Stanford University School of Medicine, Palo Alto, Calif.

Footnotes
Submitted for publication May 3, 1967.

Reprint requests to 300 Pasteur Dr, Palo Alto, Calif 94304 (Dr. Oberhelman).

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