This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (1)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Massive Gastric Bleeding Following Withdrawal of Anticoagulation Therapy

Agustin Torres, MD

AMA Arch Surg. 1968;96(2):281-283.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE LONG-term use of anticoagulants in the management of vascular disturbances has been increasingly reported as causing complications such as spontaneous bleeding,¹ paralytic ileus,² intestinal obstruction,^3-5 intoxication,⁶ and intramural hemorrhage of small intestine.^7,8 Complications due to withdrawal in long-term use of anticoagulants are mostly related to thromboembolic phenomena. The purpose of this report is to present a case of multiple thrombosis of gastric submucosa vessels producing infarctions and massive gastric hemorrhage terminating in death. The patient had been taking warfarin sodium (Coumadin Sodium), 5 mg daily, during the past seven years, after a myocardial infarction. Anticoagulants were withdrawn in order to surgically remove a recurrent and a new basal cell epithelioma of the face. Sudden severe postsurgical symptoms led to what was believed to be cerebral damage due to thrombosis of the left carotid artery. Anticoagulant therapy was resumed which apparently enhanced the gastric bleeding. . . . [Full Text PDF of this Article]

Author Affiliations
St. Louis

From the Veterans Administration Hospital, Jefferson Barracks, St. Louis.

Footnotes
Submitted for publication Aug 10, 1967.

Reprint requests to Veterans Administration Hospital, Jefferson Barracks, St. Louis 63125.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?