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Successful Total Adrenal Autotransplantation Into the Spleen of Dogs
Max E. Childress, MD;
Sanford E. Leeds, MD
AMA Arch Surg. 1968;96(3):349-358.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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IN A RECENT communication from this laboratory1, a method of diversion of the adrenal venous effluent through the portal circulation of dogs by an adrenal venous-portal shunt was described. This method was based on the technique of Leeds et al2 for transplantation of the adrenal gland. The method was not entirely satisfactory since it appeared that part of the adrenal venous flow entered the systemic circulation through collateral vessels rather than passing through the liver. In this report an improved method is described to completely divert the adrenal venous flow into the portal circulation.
Although it has been abundantly demonstrated both experimentally and clinically that alteration by the liver of the biological activity of certain steroid hormones occurs, the blood pressure of dogs with Goldblatt hypertension was not appreciably altered when adrenal venous blood was diverted through the liver.1 There were reservations, however, as to the completeness
. . . [Full Text PDF of this Article]
Author Affiliations
San Francisco
From the Harold Brunn Institute, Mount Zion Hospital and Medical Center, San Francisco. Doctor Childress was a postdoctoral research fellow of the US Public Health Service.
Footnotes
Submitted for publication June 3, 1967.
Reprint requests to the Harold Brunn Institute, Mount Zion Hospital and Medical Center, 1600 Divisadero St, San Francisco 94115 (Dr. Leeds).
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