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Use of Tissue Adhesives for Arterial Anastomoses
LTC Teruo Matsumoto, MC;
K. C. Pani, MD;
COL Harold F. Hamit, MC
AMA Arch Surg. 1968;96(3):405-409.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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CLOTTING deficiencies related to massive bleeding and transfusion, although not common, are important from the standpoint of military surgery. In situations in which clotting deficiencies cannot be corrected promptly, surgery may compound the problem and even result in death from hemorrhage. Vascular anastomoses are a particularly potential source of difficulty in these situations.
N-alkyl-alpha-cyanoacrylate monomers have been used since 1960 by many investigators as a tissue adhesive for nonsuture anastomosis of blood vessels.1-8 Previous papers from this institute9,10 presented early results and apparent success 14 weeks after the divided femoral arteries of dogs were repaired with N-alkyl-alpha-cyanoacrylate monomer adhesives.
This report describes a 14-month followup of these dogs and the use of aerosol tissue adhesive spray (normal or isobutyl cyanoacrylate with Freons as a propellant) in the suture line reinforcement of arterial anastomosis.
Materials and Methods
Femoral arteries (2.5 to 6 mm in outside diameter) in 45 mongrel
. . . [Full Text PDF of this Article]
Author Affiliations
USA; USA, Washington, DC
From the Division of Surgery, Walter Reed Army Institute of Research, Washington, DC.
Footnotes
Submitted for publication Sept 6, 1967.
Reprint requests to Division of Surgery, Walter Reed Army Institute of Research, Washington, DC 20012 (Dr. Matsumoto).
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